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TAKEDA PHARMACEUTICAL COMPANY LIMITED

(4502)
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Wave Life Sciences Ltd. Announces an Amendment to its Ongoing Collaboration with Takeda Pharmaceutical Company Limited

10/18/2021 | 05:07pm EST

Wave Life Sciences Ltd. announced an amendment to its ongoing collaboration with Takeda Pharmaceutical Company Limited, which immediately discontinues the discovery research component of the collaboration that provided Takeda with the right to license multiple preclinical programs for central nervous system (CNS) indications over a four-year research term. Under terms of the amendment, Takeda will pay Wave $22.5 million for collaboration-related research and preclinical expenses. The amendment announced allows Wave to advance CNS programs independently or enter partnerships in the CNS field outside of the three specified targets, which are part of the ongoing late-stage collaboration between the companies. The late-stage component of the original collaboration led by Wave remains unchanged, including Takeda?s option to co-develop and co-commercialize CNS therapies for three targets, C9orf72, HTT and ATXN3, including WVE-004 and WVE-003. WVE-004 and WVE-003 are currently being investigated in the ongoing Phase 1b/2a FOCUS-C9 clinical trial for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia, and the ongoing Phase 1b/2a SELECT-HD clinical trial for the treatment of Huntington?s disease, respectively. Should Takeda opt in on any of these programs, Wave would receive an opt-in payment and would lead manufacturing and joint clinical co-development activities. Takeda would lead joint co-commercial activities in the United States and all commercial activities outside of the United States. Global costs and potential profits would be shared 50:50 and Wave would be eligible to receive development and commercial milestone payments. Wave?s cash runway remains unchanged. The company expects that its existing cash and cash equivalents, together with expected and committed cash from its existing collaboration, will enable the company to fund its operating and capital expenditure requirements into the second quarter of 2023.


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Analyst Recommendations on TAKEDA PHARMACEUTICAL COMPANY LIMITED
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Financials
Sales 2022 3 407 B 30 213 M 30 213 M
Net income 2022 223 B 1 973 M 1 973 M
Net Debt 2022 3 334 B 29 566 M 29 566 M
P/E ratio 2022 21,4x
Yield 2022 5,86%
Capitalization 4 782 B 42 287 M 42 398 M
EV / Sales 2022 2,38x
EV / Sales 2023 2,25x
Nbr of Employees 47 099
Free-Float 98,2%
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Takeda Pharmaceutical Company Limited Technical Analysis Chart | 4502 | JP3463000004 | MarketScreener
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Number of Analysts 15
Last Close Price 3 070,00 JPY
Average target price 4 322,86 JPY
Spread / Average Target 40,8%
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Managers and Directors
Christophe Weber President, CEO & Representative Director
Constantine Saroukos Chief Financial Officer & Director
Andrew S. Plump Director, Research & Development President
Michael E. Mendelsohn Chief Medical & Scientific Officer
Norimasa Takeda Chief Accounting Officer & Corporate Controller
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