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  5. Sareum Holdings plc
  6. Company
    SAR   GB00B02RFS12


Delayed Quote. Delayed London Stock Exchange - 10/25 11:35:05 am
6.45 GBX   -3.73%
04:44aSAREUM : Final Results
10/21SAREUM : Notice of Results
10/07SAREUM : US Patent Granted for SDC-1802 TYK2/JAK1 Inhibitor
Business Summary
Logo Sareum Holdings plc
Sareum Holdings plc is engaged in the discovery and development of new therapeutic drugs by a combination of skills in biology, computational chemistry and medicinal chemistry. The Company's drug programs include Checkpoint Kinase 1 (CHK1), Aurora+FLT3 Kinase and Tyrosine Kinase 2- autoimmune diseases (TYK2), Aurora+FLT3 kinase and TYK2 kinase-cancer. Its Chk1 program is the advanced program and shows potency in disease models of lung and colon cancers in combination with chemotherapy; acute myeloid leukemia (AML) and B-cell lymphoma, and head and neck cancers in combination with radiotherapy. TYK2 kinase program focuses on developing a series of TYK2 inhibitors that can be dosed orally against various autoimmune and inflammatory disorders, including psoriasis and rheumatoid arthritis. Its Aurora+FLT3 Kinase program focuses on AML and other blood cancers. Its TYK2 kinase prevents T-cell acute lymphoblastic leukemia (T-ALL) cells from proliferating by causing programmed cell death.
Sales per Business
Therapeutic Drugs--0.05100%-
GBP in Million
Sales per region
United Kingdom--0.05100%-
GBP in Million
Name Title Age Since
Timothy John Mitchell, Dr. Chief Executive Officer & Executive Director 60 -
John Charles Reader, Dr. Executive Director & Chief Scientific Officer 53 2012
Clive Birch Independent Non-Executive Director 67 2018
Anthony John Bunn Secretary - -
Members of the board
Name Title Age Since
Stephen B. Parker, Dr. Non-Executive Chairman 62 2016
Timothy John Mitchell, Dr. Chief Executive Officer & Executive Director 60 -
John Charles Reader, Dr. Executive Director & Chief Scientific Officer 53 2012
Michael John Owen, Dr. Non-Executive Director 69 2018
Clive Birch Independent Non-Executive Director 67 2018
Vote QuantityFree-FloatCompany-owned sharesTotal Float
Stock A 1 3,365,701,148 3,216,776,701 95.6% 0 0.0% 95.6%
Hargreaves Lansdown Stockbrokers Ltd. 363,001,000 10.8%
Hargreaves Lansdown Asset Management Ltd. 196,659,000 5.84%
HSBC Global Asset Management (UK) Ltd. 138,169,000 4.11%
John Charles Reader 51,625,385 1.53%
Timothy John Mitchell 50,476,073 1.50%
Jarvis Investment Management Ltd. 37,926,000 1.13%
HSBC Bank Plc (Market-Maker) 25,393,000 0.75%
IG Markets Ltd. 22,613,000 0.67%
The Share Centre Ltd. 12,859,000 0.38%
KW Investment Management Ltd. 9,870,000 0.29%
Company contact information
Sareum Holdings Plc
Unit 2A, Langford Arch
London Road
Cambridge, Cambridgeshire CB22 3FX

Phone : +44.1223.497700
Fax : +44.1223.497701
Web : http://www.sareum.co.uk
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Sector Bio Therapeutic Drugs