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MERCK & CO., INC.

(MRK)
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Merck's Keytruda Hits Key Endpoint in Metastatic Triple-Negative Breast Cancer

07/27/2021 | 05:42am EDT

By Colin Kellaher

Merck & Co. Tuesday said a pivotal Phase 3 study of its cancer drug Keytruda in combination with chemotherapy met a primary endpoint of overall survival in metastatic triple-negative breast cancer.

The Kenilworth, N.J., drugmaker said the combination showed a statistically significant and clinically meaningful improvement in overall survival compared with chemotherapy alone in patients whose tumors expressed PD-L1 with a combined positive score of at least 10.

Merck said Keytruda is the first anti-PD-1 therapy in combination with chemotherapy to show statistically significant overall survival for that patient population. The company previously reported that the combination had shown significantly improved progression-free survival.

Merck is studying Keytruda, a cancer drug that harnesses a patient's immune system to fight tumors, across multiple settings and stages of triple-negative breast cancer, the subtype with the worst survival prognosis.

Write to Colin Kellaher at colin.kellaher@wsj.com

(END) Dow Jones Newswires

07-27-21 0742ET

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Analyst Recommendations on MERCK & CO., INC.
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Financials (USD)
Sales 2021 46 881 M - -
Net income 2021 12 645 M - -
Net Debt 2021 15 254 M - -
P/E ratio 2021 16,1x
Yield 2021 3,52%
Capitalization 186 B 186 B -
EV / Sales 2021 4,30x
EV / Sales 2022 3,89x
Nbr of Employees 73 500
Free-Float 70,7%
Chart MERCK & CO., INC.
Duration : Period :
Merck & Co., Inc. Technical Analysis Chart | MRK | US58933Y1055 | MarketScreener
Technical analysis trends MERCK & CO., INC.
Short TermMid-TermLong Term
TrendsBearishBearishBearish
Income Statement Evolution
Consensus
Sell
Buy
Mean consensus BUY
Number of Analysts 22
Last Close Price 73,61 $
Average target price 93,42 $
Spread / Average Target 26,9%
EPS Revisions
Managers and Directors
Robert M. Davis President, Chief Executive Officer & Director
Caroline A. Litchfield Chief Financial Officer & Executive Vice President
Kenneth C. Frazier Executive Chairman
Sandy Tremps Vice President-R&D IT CIO
Dave Williams Chief Information & Digital Officer
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