Log in
Show password
Forgot password ?
Become a member for free
Sign up
Sign up
New member
Sign up for FREE
New customer
Discover our services
Dynamic quotes 
  1. Homepage
  2. Equities
  3. Japan
  4. Japan Exchange
  5. HORIBA, Ltd.
  6. News
  7. Summary
    6856   JP3853000002


SummaryMost relevantAll NewsOther languagesPress ReleasesOfficial PublicationsSector news

HORIBA : Shimadzu and HORIBA Release LC-Raman System

08/18/2021 | 04:44am EDT

Merging Separating and Visualizing Technologies Offers New Value for R&D Applications in a Wide Variety of Fields

On June 25, 2021, Shimadzu Corporation (Kyoto, President & CEO: Teruhisa Ueda, hereinafter Shimadzu) and HORIBA, Ltd. (Kyoto, President & COO: Masayuki Adachi, hereinafter HORIBA) released a new LC-Raman system that combines a Shimadzu high-performance liquid chromatograph (HPLC, hereinafter LC) with a HORIBA Raman spectrometer (hereinafter Raman) for the Japanese domestic market.
The product is the result of joint development work that started in August 2020 and represents the world's first* system to combine these technologies. Combining LC separation technology with Raman visualization technology not only significantly increases measurement accuracy and efficiency, it is expected to offer new measurement value by detecting unknown components.
Both companies intend to contribute to global society by releasing superior technologies from Kyoto out to the world.

Development Background

Markets involved in ensuring the safety and health of people, such as healthcare, pharmaceuticals, and life sciences, and markets involved in developing advanced materials, have been changing at a rapid pace in recent years. For research and development in such fields, it is important to have measuring methods that are as accurate and efficient as possible.
Shimadzu liquid chromatographs provide superior 'separation' technology for isolating target measurement components from sample mixtures, which is a key strength for accurate quantitative analysis of target components. HORIBA Raman spectrometers provide superior 'visualization' technology for discriminating between different molecular structures, which is a key strength for predicting unknown components. Both products have the largest share* of their respective product markets in Japan. In an effort to further accelerate innovation, both companies jointly developed a new LC-Raman system by combining the strengths of their respective technologies to achieve a new dimension of performance.

* According to a survey by both companies (as of June 2021)

Product Features

1. 'Sharp' Differentiation: Clearly Identifies Constituents in Mixture Samples
• The LC unit efficiently separates constituent components from mixture samples and concentrates each component by dripping them onto a plate. Then the Raman acquires the Raman spectrum for each component. The respective components are identified by comparing the resulting Raman spectrum to spectra registered in a database. That results in ultra-accurate discrimination that is over 100 times more accurate than conventional Raman spectrometers, which contributes to measuring compounds with complex structures or detecting unknown components.

2. Specialized Software Promotes Easy Operation and Centralized Data Management
• Dedicated LiChRa software integrates LC and Raman operation. In addition to controlling overall instrument operation, LiChRa software provides centralized management of data from the LC and Raman units linked to sample information. Furthermore, the simple and intuitive window layout ensures easily understandable operation, even for first-time users. It also makes it easy to view and search measurement results and other data in one location.

3. Using the System for a Wide Variety of Analytical Applications
• Professor Haruko Takeyama, Faculty of Science and Engineering, Waseda University is working with the two companies to develop applications in the life science and bioscience markets. It will be offered as a solution for challenges in a wide variety of measuring situations, including based on synergies in industry-academia collaborations.
• Shimadzu and HORIBA also developed a method for analyzing the structure of synthetic polymers with the LC-Raman system.

Examples of Anticipated Applications
Field Application
Healthcare • Biomarker discovery
• Analyzing components in biological organisms
Pharmaceuticals • Analyzing structural isomers of small-molecule drugs
• Analyzing aggregates and modified groups in antibody drugs
Life Sciences • Analyzing/discovering microorganism metabolites
(building a metabolite database and searching for new substances)
• Analyzing components in culture media
Foods • Analyzing the ratios of sugars and fatty acids in compositions
• Searching for new components with functional benefits
Chemical Products • Predicting the structure of synthetic compounds and evaluating impurities
• Analyzing structural changes in components of cosmetics, etc.

Note: Currently, the system is only available in Japan

High-performance liquid chromatograph:
An instrument or system that performs high-performance liquid chromatography (HPLC). HPLC systems are used to qualitatively or quantitatively analyze individual sample components by pumping the mobile phase solution and the sample through a column (a long tube) to separate the respective components and then using a detector to detect the separated components after they exit the column.
Raman spectrometer:
A system that analyzes substances using Raman spectroscopy based on the properties of light. Raman spectrometers irradiate samples with monochromatic light and then detect the Raman light scattering characteristics uniquely exhibited by each substance in order to analyze the molecular structure or component content of samples or to evaluate the stress, strain, or other properties.

From the left is Kyoko Watanabe, Product Manager, LC Business Unit, Analytical & Measuring Instruments Division, Shimadzu; Masami Tomita, Deputy General Manager, Analytical & Measuring Instruments Division, Shimadzu; Professor Haruko Takeyama, Faculty of Science and Engineering, Waseda University ; Kentaro Nishikata, General Manager, R&D Division, HORIBA; and Mikiko Uchigashima, Deputy Project Manager, Bio/Life Science Project, HORIBA


Horiba Ltd. published this content on 18 August 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 18 August 2021 08:43:09 UTC.

ę Publicnow 2021
All news about HORIBA, LTD.
03:32aHORIBA : Posted the presentation material for "SMBC Nikko Japan Series ESG Conference Lond..
10/14HORIBA : Veterinary haematology CPD webinar hosted by HORIBA to offer valuable best...
10/06HORIBA : Development of the Partica CENTRIFUGE CN-300, Centrifugal Nanoparticle Analyzer ...
10/04HORIBA : Scientific Validates the HORIBA Aqualog« Performance for Pharmaceutical...
09/28VELODYNE LIDAR : Intelligent Traffic Monitoring Solution Chosen for Deployment at the Univ..
09/28HORIBA : Sepsis and COVID - Clinical Cases of Yumizen H2500 Hematology Analyzers "Chase...
09/16HORIBA : Scientific Partners with Covalent Metrology to Offer Glow Discharge...
09/13WORLD SEPSIS DAY 2021 : time is of the essence
09/12HORIBA : Posted the presentation material for online conferences (Q2 2021)
09/03HORIBA : Burkitt lymphoma - HORIBA Medical QSP Newsletter 16
More news
Sales 2021 219 B 1 913 M 1 913 M
Net income 2021 20 269 M 177 M 177 M
Net cash 2021 37 969 M 332 M 332 M
P/E ratio 2021 16,0x
Yield 2021 1,75%
Capitalization 324 B 2 839 M 2 836 M
EV / Sales 2021 1,31x
EV / Sales 2022 1,24x
Nbr of Employees 8 269
Free-Float 91,6%
Duration : Period :
HORIBA, Ltd. Technical Analysis Chart | 6856 | JP3853000002 | MarketScreener
Technical analysis trends HORIBA, LTD.
Short TermMid-TermLong Term
Income Statement Evolution
Mean consensus OUTPERFORM
Number of Analysts 9
Last Close Price 7 680,00 JPY
Average target price 8 337,50 JPY
Spread / Average Target 8,56%
EPS Revisions
Managers and Directors
Atsushi Horiba Chairman & Group Chief Executive Officer
Masayuki Adachi President & Representative Director
Sunao Kikkawa General Manager-Finance & Control Division
Juichi Saito Vice Chairman & Group Chief Operating Officer
Masao Okawa Managing Director & General Manager-Administration
Sector and Competitors
1st jan.Capi. (M$)
HORIBA, LTD.26.94%2 796
RENISHAW PLC-19.93%4 585