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    4503   JP3942400007

ASTELLAS PHARMA INC.

(4503)
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Astellas Launches Kiklin Granules, Treatment for Hyperphosphatemia in Japan

12/07/2016 | 06:30am EDT

Astellas Pharma Inc. announced that it launched Kiklin Granules 86.2% (generic name: bixalomer, ‘Kiklin Granules’), an additional formulation of Kiklin Capsules 250 mg (‘Kiklin Capsules’), for the indication of treatment of hyperphosphatemia in patients with chronic kidney disease (‘CKD’) in Japan today. Astellas expects to further contribute to hyperphosphatemia treatment by introducing Kiklin Granules which can further improve the compliance with its more convenient dosing option into Japanese market. Hyperphosphatemia occurs in patients whose renal function is decreased, since phosphorus is not sufficiently excreted into urine via the kidneys and consequently accumulates in the body. With continuous high blood phosphorus concentration, the risk of renal osteodystrophy characterized by a high tendency of bone pain and bone fracture is known to be increased. Additionally, high blood phosphorus concentration is associated with increased coronary artery calcification and subsequent cardiovascular events. Therefore, it is considered extremely important to maintain the serum phosphorus concentration at an appropriate level in CKD patients. Bixalomer is amine-functional polymers which decrease the serum phosphorus concentration by binding to phosphate in the gastrointestinal tract, thus inhibiting absorption of phosphate into the human body.


ę S&P Capital IQ 2016
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Financials
Sales 2022 1 325 B 11 902 M 11 902 M
Net income 2022 194 B 1 747 M 1 747 M
Net cash 2022 478 B 4 290 M 4 290 M
P/E ratio 2022 17,7x
Yield 2022 2,67%
Capitalization 3 474 B 31 313 M 31 211 M
EV / Sales 2022 2,26x
EV / Sales 2023 1,90x
Nbr of Employees 15 455
Free-Float 98,9%
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Astellas Pharma Inc. Technical Analysis Chart | 4503 | JP3942400007 | MarketScreener
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Mean consensus BUY
Number of Analysts 13
Last Close Price 1 875,00 JPY
Average target price 2 451,54 JPY
Spread / Average Target 30,7%
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Managers and Directors
Kenji Yasukawa President, CEO & Representative Director
Naoki Okamura CFO, Representative Director & Vice President
Yoshihiko Hatanaka Chairman
Yoshitsugu Shitaka Chief Scientific Officer
Fumiaki Sakurai Head-Business Administration & Compliance
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